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Bio3 Seminar Series with Shuangge Ma, Ph.D.
|Event||Bio3 Seminar Series with Shuangge Ma, Ph.D.|
|When||Friday, September 13, 2013 from 10:00am to 11:00am|
|Where||Building D Warwick Evans Conference Room|
Speaker: Shuangge Ma, Ph.D., Associate Professor of Public Health (Biostatistics), Yale University
Title: Contrasted Penalized Integrative Analysis
Abstract: Single-dataset analysis of high-throughput omics data often leads to unsatisfactory results. The integrative analysis of heterogeneous raw data from multiple independent studies provides an effective way to increase sample size and improve marker selection results. In integrative analysis, the regression coefficient matrix has certain structures. In our study, we use group penalization for one- or two-dimensional marker selection and introduce contrast penalties to accommodate the subtle coefficient structures.
Simulations show that the proposed methods have significantly improved marker selection properties. In the analysis of cancer genomic data, important markers missed by the existing methods are identified.
|Access||» This event is limited to Georgetown University students, faculty and staff.|
|Contact||Lindsay Seidenberg, firstname.lastname@example.org|
|Sponsors||Department of Biostatistics, Bioinformatics and Biomathematics|
|Web site||For more information, see http://dbbb.georgetown.edu/seminar/fall2013/|
Department of Biostatistics, Bioinformatics and Biomathematics
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