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Bio3 Seminar Series with Shuangge Ma, Ph.D.
Schedule information
Event Bio3 Seminar Series with Shuangge Ma, Ph.D.
When Friday, September 13, 2013 from 10:00am to 11:00am
Where Building D Warwick Evans Conference Room
Event details
Details Speaker: Shuangge Ma, Ph.D., Associate Professor of Public Health (Biostatistics), Yale University

Title: Contrasted Penalized Integrative Analysis

Abstract: Single-dataset analysis of high-throughput omics data often leads to unsatisfactory results. The integrative analysis of heterogeneous raw data from multiple independent studies provides an effective way to increase sample size and improve marker selection results. In integrative analysis, the regression coefficient matrix has certain structures. In our study, we use group penalization for one- or two-dimensional marker selection and introduce contrast penalties to accommodate the subtle coefficient structures.
Simulations show that the proposed methods have significantly improved marker selection properties. In the analysis of cancer genomic data, important markers missed by the existing methods are identified.
Access » This event is limited to Georgetown University students, faculty and staff.
Contact Lindsay Seidenberg, lcb48@georgetown.edu
Sponsors Department of Biostatistics, Bioinformatics and Biomathematics
Web site For more information, see http://dbbb.georgetown.edu/seminar/fall2013/
Calendar Department of Biostatistics, Bioinformatics and Biomathematics
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